Franklin Bache (October 25, 1792 – March 19, 1864) was an American physician, chemist, professor and writer from Pennsylvania.

He left medical school in 1813 and entered the United States Army as a surgeons mate in an infantry division during the War of 1812.

In 1822, he succeeded Gerard Troost as professor of chemistry at the Philadelphia College of Pharmacy and became the chair of materia medica from 1831 to 1841.

[3] He partnered with Dr. Robert Hare and edited the American version of Andrew Ure's Dictionary of Chemistry.

While working at the state penitentiary, he treated 12 different prisoners with various ailments including muscular rheumatism, chronic pain, neuralgia and ophthalmia.

He served as vice-president of the College of Physicians of Philadelphia[4] and as president of the deaf and dumb asylum corporation.

[4] Bache died of typhoid fever[10] on 19 March 1864 in Philadelphia[11] and was interred at Laurel Hill Cemetery.