Fred Hofmann (June 10, 1894 – November 19, 1964), nicknamed "Bootnose", was an American professional baseball player, coach, scout and manager.

He started at a professional level with the Cedar Rapids Kernels of the Central Association in 1915, then he served in the U.S. Navy during World War I from 1918 through 1919.

Following his service discharge, Hofmann entered the majors in 1919 with the New York Yankees, sharing duties with Muddy Ruel and Wally Schang.

During the 1925 midseason, Hofmann was sent by the Yankees to the St. Paul Saints of the American Association in the same transaction that brought Mark Koenig to New York.

Two of his top finds for the Orioles were All-Star slugger Boog Powell and pitcher Wally Bunker, who won 19 games during his rookie season.