[1][2][3][4] https://pmc.ncbi.nlm.nih.gov/articles/PMC10731624/ Freiberg disease is a rare condition that affects the second metatarsal head, leading to pain and potential deformity.

The process typically begins with a disruption of blood supply to the metatarsal head, leading to avascular necrosis of the bone tissue.

[5] https://journals.sagepub.com/doi/10.1177/19476035231205676 Accurate diagnosis of Freiberg disease typically involves a combination of clinical examination and imaging studies: Differential diagnosis is important, as several conditions can mimic Freiberg disease, including stress fractures of the metatarsal, Morton's neuroma, and various forms of arthritis.

Options include: Nonoperative Management Freiberg disease is relatively rare, but it is more commonly diagnosed in young females, particularly those involved in sports or activities that place repetitive stress on the forefoot.

Early diagnosis and appropriate management can lead to favorable outcomes, with many patients experiencing significant pain relief and improved function.

However, some individuals may develop chronic pain or limitations in physical activities, particularly if the condition is left untreated or progresses to advanced stages.