During the Cold War, they were primarily used to patrol the continental shelf of the Atlantic Ocean in search of Soviet Navy submarines.

In January 2013, during Operation Serval in Mali, Enseigne de vaisseau Jacoubet escorted the ro-ro vessel MN Eider chartered by the French Navy, which was transporting equipment to Senegal.

[6] On 15 February 2019, the vessel joined the European operation EU Navfor Med in order to fight against trafficking in the Mediterranean.

[8] In 2022, it was indicated that the ship would be equipped with the SMDM (navy mini-drone system) to enhance her surveillance capabilities.

[9] Enseigne de vaisseau Jacoubet is scheduled to be withdrawn from service in 2026 and be replaced by one of a new class of ocean-going patrol vessels (the Patrouilleurs Hauturiers).