In November 2006 and again in June 2010, Latouche-Tréville visited London on diplomatic duties, and was moored alongside the Second World War cruiser, HMS Belfast.

On 18 April 2015, she escorted a replica of the 18th century sailing ship Hermione as it departed La Rochelle, France on her maiden voyage across the Atlantic to Yorktown, Virginia in the United States.

[5][6] In May, Latouche-Tréville was among a dozen surface vessels and four submarines that took part in NATO's annual "Dynamic Mongoose" military exercise.

Amid rising tensions with Russia, the two-week event in Norwegian waters saw ships under NATO command conducting a variety of anti-submarine warfare operations.

On 9 January 2020, the vessel suffered damage in a storm soon after departing from Brest, and returned to port the next day with her top mast missing.