Commissioned under Captain Bernard Dubourdieu in November 1806, Pénélope served in the Atlantic for some months.

On 21 January 1808, along with Thémis, she departed Bordeaux for a cruise to Toulon.

They arrived on 28 March, having captured 12 British prizes en route, including the privateer Sirene.

Pénélope was decommissioned at the Bourbon Restoration, on 31 August 1815, and was sold for scrap in 1828.

This article about a specific military ship or boat of France is a stub.