The Friends Meeting House and Cemetery is a historic Quaker meeting house and cemetery at 228A W. Main Road in Little Compton, Rhode Island.

The meeting house is a two-story wood-frame structure built in 1815 by the Religious Society of Friends, commonly known as Quakers, on the site of their first meeting house built in 1700 on land granted to John Irish.

The new meeting house used some materials from the original one.

[2] The meeting house was used by Quakers until 1903, and was maintained by members of the Apponegansett Meeting House in Dartmouth, Massachusetts until 1946, when it was donated to the Little Compton Historical Society.

[2] The meeting house and cemetery were listed on the National Register of Historic Places in 2007.