It forms part of the franchise of film, direct-to-video, and comics of From Dusk till Dawn, expanding on the chronicles of the Gecko Brothers, Seth and Richie, the Fuller family, and Santanico Pandemonium.

[2] The series also references the Popol Vuh, drawing on its rich, mythological history and, in particular, on the legend of the Hero Twins Hunahpú and Xbalanqué to add greater depth to the backstories and to fully flesh out the characters of the show's protagonists.

[11] In this supernatural crime series, Seth Gecko and his violent, unpredictable brother, Richard "Richie" Gecko, are wanted by the FBI and Texas Ranger Freddie Gonzalez after a bank robbery left several people, including policemen and Gonzalez's mentor Texas Ranger Earl McGraw, dead.

Drug lord Don Carlos reroutes them to a strip club populated by snakelike people that all must fight for food to survive until dawn.

Series creator and showrunner Rodriguez, who also directed the pilot and other episodes, stated the original film is "one of the favorite movies that I did in the past with Quentin Tarantino and one that people still ask us about today.