In the main town of Grovetown, Maryland, high school girl Lindsay is shopping with her stepmother, Trish, for new church clothes.

Bernard knocks down the door, only to find Natalie dying, with a pair of scissors lodged into her neck.

That night Bernard is haunted by a ghostly figure and is found dead the following day by his niece Molly, hanged in the same room Natalie died in.

The following day, Lindsay's best friend Claire drives past Molly's body, and immediately begins to hear voices.

Simultaneously, Lindsay becomes aware of the religious fervor Dylan is stirring up against Aidan among the townsfolk, and goes to warn him of the danger.

On entering his house, she meets his cousin, Sadie, who had traveled down from New York for Sean's funeral.

Aidan takes Lindsay to a stream running underneath a bridge, and confirms that his mother practiced a form of witchcraft, which may be the cause of the suicides.

Returning home that night, Trish is jubilant about "being saved", but is later haunted by doppelgängers of herself on the television.

After being stalked throughout the house, Trish's doppelgänger compels her to drink drain cleaner, believing it to be whiskey.

Lindsay finds Trish's body and she rushes to Aidan's house, frantic in her belief that a curse has gotten inside of her and will demand her death.

Back at the home Roy tells Sadie how he became a religious man and then sets her alight with gasoline, claiming that he is doing God's will.

In July 2007, director Phedon Papamichael was hired to direct From Within, a thriller based on a script by Brad Keene.

[1] The writer described the film: "I wanted to write something that was scary and high concept and dealt with personal issues, namely religious beliefs and how they play a part in who we are and the way we lead our lives.

For From Within, filming took place in Perry Point, Maryland, a defunct estate with homes that would be torn down after the completion of production.