Frontignan (French pronunciation: [fʁɔ̃tiɲɑ̃]; Occitan: Frontinhan) is a commune in the Hérault department in southern France.

Frontignan is located in the Languedoc coastal plain between the towns of Sète and Montpellier.

The town is surrounded by the Gardiole hills to the north, the Ingril lagoon in the east, the Étang de Thau to the west and the Mediterranean shore (including the beach resort Frontignan-Plage) to the south.

Frontignan station has rail connections (TER Occitanie) to Narbonne, Montpellier and Avignon.

Until the early 20th century the local economy was based on the production of marine salt and wine.