The club was founded on 5 March 1906 under the name Unione Sportiva Frusinate,[2] but conventionally the year 1928 is indicated as the beginning of competitive activities of significant importance.

The association has as its main purpose the diffusion among the younger generations of gymnastic disciplines, fencing, football and athletic sports with the aim of physical and intellectual education of Frosinone youth."

Councilors: student R. Giovannelli - accountant G. Tora - receiver G. Pesci - engineer E. Marzi - Inspector E. Toscano - Secretary Gabriele Antonucci - Sports Director Gerardo Bodin de Chadelard».

[3] The presence of competitive football-related activities is demonstrated by some documents immediately following the signing of the company statute, including a photo dating back to 1907, taken from the Bottoni archive, which shows a youth team of Frosinone footballers probably aged between 10 and 12 years.

Il Messaggero underlined, in the edition of 1 February 1907, the feedback acquired in a short time by the new sports association in the city: «This sports union which has as its main purpose physical education, given the ever increasing number of members , has occupied new premises [...] The brilliant meeting is frequented by the most respectable people of the city who praise and encourage the healthy development of the Association».

[5] It showed a rampant lion on a red background and a blue cross band with the motto "Bellator Frusino", given by Sillo Italico, when the city refused to surrender to Hannibal's armies.

[citation needed] Article III of the Articles of Association stated, with a rather modern approach for the time, that the sports association abstained from any activity of a political and religious nature The first playing field adopted by the company was located in Frosinone along today's via Cicerone (at the time called via Casilina Nord) near the municipal villa, while the historic "Stadio Matusa" (which would have resisted, with modifications and extensions subsequent, until 2017) was built only in 1932.

In fact, even before the change of company name induced by the fascist regime, the U.S. Frusinate had already obtained affiliation with the FIGC in 1923 and had been involved in competitive activity by appearing in the federal ranks of the championship of the Fourth Division Lazio 1923–1924 in group B.

The Ciociaro team in that period at an organizational level was coordinated by Augusto Diamanti, a reference figure who was in charge of the company's executives.

In the starting lineup, among others: Biagi (goalkeeper), Armando Niro, Nobili, Magni, Luigi Diamanti, Dante and Giulio Toscani, Aldo and Renato Calmanti (the latter would also be captain for many years to come, also playing in the Prima Division until the mid-1930s, when he suddenly died of a heart attack at the age of 29).

The official meeting, directed by the referee Carlo Magni and played in the presence of the mayor Piero Gizzi and the military authorities, was valid for the assignment of the Comune di Frosinone award.

Experienced players such as Vincenzo Fresia, four-time champion of Italy with Pro Vercelli and former number 9 jersey in the national team were lined up in the latter's row.

[4] At that time the presence of category players in the military selection stimulated the competitive activity of the Unione Sportiva Frusinate, which was deployed on the field with the white and blue social colors.

On 17 October 1929 the sports newspaper Il Littorale reported the news of the affiliation of the new Polisportiva Bellator Frusino to the FIGC.

From 1952 to 1958, for six consecutive years, the Canarini competed in the Quarta Serie Championship, with their highest finish being fourth place, which was achieved in 1953.

The most important people of this time were the presidents Domenico Ferrante and Angelo Cristofaro (one of the leading figures in the history of the club), a former coach Genta and players Azzoni, Gabriele, Diglio, Dini and Spinato.

The leading figures at the club during this period were the Stirpe brothers, coaches De Angelis and Rambone and players Benvenuto, Caputi, Da Col, Del Sette, Fumagalli and Trentini.

Despite a precarious financial condition, Frosinone led by president Di Vito and coach Alberto Mari were promoted to Serie C1.

Goalkeeper Marco Cari and coach Alberto Mari (later replaced by Robotti) were suspended for a football related betting offence.

Among the most important players during the 1980s were Davato, Atzori, Di Liso, Cristiano, Bellini, Perrotti and Edoardo Artistico Poli, who then began an enviable football career.

In 1993–94, after the championship was almost completed, the Canarini ("the canaries") were overtaken by both Giulianova and Albanova, and were relegated, but they were reinstated to Serie C after the season ended.

In 1996 the club gained a mid-table placing in Serie C2, and was leading in Girone C of C2, but on the last day of the championship Frosinone was defeated by Benevento and was overtaken in the table by Avezzano.

Upon their return to C1, which saw them travel to such historic cities as Cremona, Mantua, and Pisa, Frosinone appointed Dino Pagliari as coach, while the likes of Salvatore Mastronunzio, Di Deo (later sold to Ternana in B), Molinari, Nicola Pagani, Mauro Zaccagnini, goalkeeper Zappino, promoted, Alfredo Cariello, Davide D'Antoni, Francesco Mocarelli, Antonio Di Nardo, Michele Ischia were all signed to bolster the playing squad.

In the following season, 2005–06, Frosinone were coached by Ivo Iaconi, who had offers from two Serie B teams, Fermana and Pescara, yet opted to manage the Canarini.

The goal from Alessandro Del Piero (his 200th for Juve) decided the game, however the Frusinati returned home with their heads held high.

On 7 June 2014, Frosinone, under the guidance of head coach Roberto Stellone, was promoted from Lega Pro Prima Divisione to Serie B after winning the playoff 1–1, 3–1 (4–2 aggregate) against Lecce.

On 16 May 2015, Frosinone won automatic promotion after a 3–1 home win against Crotone, six points ahead of third-placed Bologna with only one game remaining; as such, the club made its first Serie A appearance ever in the 2015–16 season.

[10] Frosinone's maiden Serie A campaign began in a difficult style, losing their first four outings and dropping to bottom place in the table.

Defying all odds, Frosinone came away with their first ever Serie A point thanks to an equalising last minute Leonardo Blanchard header to end the match in a 1–1 draw.

Frosinone went on to pick up their second and third consecutive home wins by beating Sampdoria by the same scoreline as Empoli and fellow newly promoted side Carpi 2–1.