Fryazino (Russian: Фрязино, IPA: [ˈfrʲæzʲɪnə]) is a scientific town in Moscow Oblast, Russia, located on the Lyuboseyevka River, a tributary of the Vorya, 25 kilometers (16 mi) northeast of the city of Moscow.

In 1584–1856, the villages of Grebnevo, Fryazinovka, and Chizhovo stood on the territory occupied by modern Fryazino.

The first mention of Fryazino was in the 1584–1586 cadastres of Moskovsky Uyezd: "Villages of Fryazinova and Samsonov as well on the river of Lyubosivka, and it includes plowed gray land tillage 4 desiatinas and of fallow 13.5 desiatinas in the field and the same in two (implying: cultivated fields), hay 10 haycocks, firewood forest, 5 acres" (Russian: дер.

на Любосивке, а в ней пашни паханые серой земли 8 четьи да перелогу 27 четв.

The first Research Institute SRI-160 (its modern name is Federal State Unitary Enterprise RPC "Istok") was founded in Fryazino in 1943, then their number increases to five.

On the eastern outskirts of the town, on the banks of the Lyuboseyevka river, is the historic estate of Grebnevo (1780–1790; reconstructed in 1817-1823).

Another monument is "Stella wins" that indicates the names of all of residents Fryazino who participated in World War II.