[8][9] The 1930 Santa Fe depot serves as an Amtrak ticket office and passenger waiting area and has a cafe.

It features Spanish Colonial Revival style architecture, as evidenced by the stuccoed walls, red tile roof, and decorative wrought ironwork.

[13] This helped firmly establish Fullerton as the regional rail center for northern Orange County.

[13] Pacific Electric constructed an interurban railway to Fullerton in 1917, terminating just north of the Santa Fe station and provided a transfer point to their system.

In the late 1990s, the Fullerton Railway Plaza Association (FRPA) began fundraising and lobbying for the creation of an interactive railroad attraction or museum at the site,[16] while continuing preservation efforts.

[18] The station is served by the Metrolink 91/Perris Valley Line and Orange County Line commuter rail services, plus Amtrak intercity Pacific Surfliner and long-distance Southwest Chief services however, all Southwest Chief trains going to Los Angeles stops only to discharge passengers while trains going to Chicago stops only to pick up passengers.