[4] He remained close to the circles of power all his life (President Herbert Hoover and his wife attended the wedding of Lewis to Alice Huston, who was the daughter of former Republican National Committee chairman Claudius Hart Huston)[1] He was an indifferent student; he attended the University of Virginia for three years (where he was a member of the Virginia Glee Club[5] and wrote the music for that school's official fight song, The Cavalier Song[6]).

The head of Washington AM radio station WOL was impressed with Lewis' "on-the-spot" reporting and offered him a full-time position.

At his commercial peak, Lewis was heard on more than 500 radio stations and boasted a weekly audience of sixteen million listeners.

He also transitioned briefly to television in the early 1950s but the format of his program did not appeal in that medium, so he returned to radio for the remainder of his career.

He first made his mark by opposing the New Deal policies of Franklin Delano Roosevelt (although he initially admired the man upon his first election), and as the world lurched toward World War II in the late 1930s he strongly supported the America First Committee, along with famed aviator Charles Lindbergh in their efforts to keep the US out of what he considered "the European War".

He was one of the first broadcasters to expose Julius and Ethel Rosenberg as the communist spies that the Venona papers proved they were, although he was later accused of antisemitism as well.

He continued on air, however, until his death in 1966, after which his son Fulton Lewis III kept the broadcast running for another twelve years.

Among those who worked for Lewis was Kenneth Tomlinson, future head of the Corporation for Public Broadcasting (CPB).

Fellow radio personality Paul Harvey broadcast a eulogy on August 22, 1966 saying "Fulton Lewis, Jr. believed in government by the people.