Replacing Animal Research was founded as FRAME by Dorothy Hegarty, who was introduced to the Three Rs by the biologist Charles Foister.
[1] Replacing Animal Research had a starting fund of £100 and was first based in a room in the Hegarty house in Wimbledon, London.
Soon, enough funds were available for FRAME to rent a shop in Worple Rd, Raynes Park, London where it was based for almost a decade.
1995 - The FRAME office relocated to the newly built Russell & Burch House, Nottingham.
[4] 2013 - Dr Anna Cadogan took over as Acting Chair of Trustees following the resignation of Professor Michael Balls.
2021 - FRAME joins the Alliance for Human Relevant Science[5] 2022 - FRAME joins The Coalition to Illuminate and Address Animal Methods Bias[6] 2024 - As part of The Coalition to Illuminate and Address Animal Methods Bias, FRAME wins a Lush Prize for Major Science Collaboration[7] Replacing Animal Research receives no direct funding from local or central government and relies entirely on donations, legacies and corporate support.