Being one of the main arteries of the Danish railway network, it has double track and is fully electrified.

[5] The Copenhagen–Roskilde railway line was prolonged from Roskilde to the port city of Korsør by the Great Belt in 1856.

[9] In Middelfart, passengers could catch the steam ferry across the Little Belt to Snoghøj in the Jutland peninsula.

The following year, on 1 november 1866, a short branch line, the Middelfart–Strib railway line, opened from Middelfart to the harbour at Strib 5 kilometers north of Middelfart, from where there was connection via railway ferry across the Little Belt to Fredericia in Jutland.

[10] In 1935, with the opening of the Little Belt Bridge between Middelfart and Snoghøj, The Funen Main Line was connected directly to the railway network in Jutland at Fredericia.