The film centres on Jungle Jim venturing into tribal land with pilot Ronald Cameron in search of Professor Dunham, who in turn is tracking down a rumoured creature known as the Okongo.

The agile explorer rescues the injured pilot, Ronald Cameron (William Henry), from the deep waters.

Cameron tells Jim that he is trying to find missing biochemistry professor Dunham, under the University of Cairo's request.

The Okongo, half-antelope and half-zebra, is greatly revered by the tribal natives of Congo and its glands are rumoured to contain a rare type of drug.

They encounter a sandstorm and Jim engages in a battle with a gigantic desert spider, before returning to save Dunham's life.

[2] The Hollywood Reporter wrote in its commentary of the film that "Fury of the Congo packs enough excitement and color to please the juvenile and action fans."

Variety commented that it was "mediocre filler fare at best", while the Motion Picture Herald described it as "largely juvenile in appeal".