On October 26, 2015, Lovato and Jonas announced on the Elvis Duran Show after days of rumors that they would go on tour together.

[13] On June 29, 2016, Lovato announced that CAST Centers would join her on tour to promote open dialogue about mental health and wellness, also to inspire fans and erase the stigma around asking for help.

Mike Posner served as the main opening act with the exceptions of Atlanta, Sunrise, Orlando, San Jose, Portland, and Seattle.

Lovato and Jonas were scheduled to perform Charlotte and Raleigh, but cancelled over the HB2 law in North Carolina.

Selena Gomez was an original headliner, but cancelled due to anxiety and depression caused by lupus.