Güer Aike Department is a department in Santa Cruz Province, Argentina.

The seat of the department is in Río Gallegos which also has the majority of the population with 97,742.

Veintiocho de Noviembre has the next largest population with 6,145 inhabitants.

The name means 'large camp' in the aonikenk (or 'tehuelche') language of southern Patagonia.

This article about a place in Santa Cruz Province, Argentina is a stub.