Shortly after graduating, Weisberg began his teaching career in art history at the University of New Mexico until 1969.

Three years later, Weisberg was hired as a professor of art history at the University of Minnesota, where he would spend the rest of his career.

[4] The publication included thirty essays from art historians, who were colleagues or students of Weisberg.

At the end of that year, the Minneapolis Institute of Art exhibited nineteenth- and twentieth-century Realist drawings from the collection of Weisberg and his wife, Yvonne.

[5] Throughout his career, Weisberg has published extensively within the field of art history and has studied artists in-depth such as François Bonvin, Léon Bonvin, and Félix Bracquemond, and topics such as Artistic Japan and Japonisme.