Pescucci gained prominence for her collaborations with directors Pier Paolo Pasolini, Federico Fellini, Sergio Leone, Terry Gilliam, Martin Scorsese, Tim Burton, and Neil Jordan.
[1][4] She began her career as an assistant to Piero Tosi on the sets of Pasolini's Medea and Visconti's Death in Venice.
[5] Pescucci took her first steps in cinema with Giuseppe Patroni Griffi at the start of the 70s, designing costumes that took inspiration from paintings by Carpaccio and Leonardo.
[4] Her international debut was in 1984 with Once Upon a Time in America, for which she won the first of her two BAFTA Awards, the second being for The Adventures of Baron Munchausen by director Terry Gilliam and production designer Dante Ferretti.
[7] Some of her most popular works include costume design on Charlie and the Chocolate Factory, Les Misérables and Agora.