Galen is a town in Wayne County, New York, United States.

[4] The Town of Galen is on the south border of the county and west of Syracuse, New York.

The primary postal district covering the Town of Galen is ZIP Code 14433 for Clyde.

The town was part of a tract set aside for physicians and surgeons of the Colonial Army as part of the Central New York Military Tract used to pay soldiers of the American Revolution.

Galen was formed from the Town of Junius in Seneca County in 1812 and became part of Wayne County in 1823, but lost part of its area to form the Town of Savannah in 1824.

[6][7] The town is part of the Erie Canalway National Heritage Corridor.

The Erie Canal passes through the town, incorporating part of the Clyde River.

24.3% of all households were made up of individuals, and 11.4% had someone living alone who was 65 years of age or older.