In 2006, the museum cared for a growing collection of over 20,000 artifacts and 300,000 archival documents and photographs record the history of Lethbridge and southern Alberta.

The building was originally located about 30 metres inside the west boundary of Galt Gardens, opposite 118 5 Street South.

The museum quickly outgrew its space and within three years had moved into the considerably renovated former Galt Hospital.

The Sir Alexander Galt Museum and Archives was operated until 1971 by The Lethbridge and District Historical Society.

[4] The naming represents a step on an important journey of working collaboratively with the Niitsitapi community and walking the path of reconciliation together.

The Galt has since been awarded with recognitions for excellence in programming, curation, marketing and tourism initiatives, horticulture and archival and collections management, including the following:[5]