Gambo is a town and designated place in the Canadian province of Newfoundland and Labrador.

Located in the northeastern portion of the island of Newfoundland on Freshwater Bay, it is in Division No.

Gambo is the closest town to Mint Brook, the birthplace of Joey Smallwood, former premier of Newfoundland and last father of confederation.

The name Gambo is said by M. F. Howley to be a corruption of a Spanish or Portuguese name that meant "bay of does".

[1] Gambo is known for its Smallwood Days and its Loggers' Sports Festival.