García Fernández Manrique y Toledo, 3rd Count of Osorno[1] (c. 1483–1546) was a Spanish nobleman.
He was president of the Council of the Indies, a position he held until his death in 1546.
In 1503, the Count married Juana Enríquez, Lady of la Vega and Ruy Ponce, who died the same year.
In 1504 he married for a second time with Juana de Cabrera y Bobadilla, daughter of Andrés de Cabrera, 1st Marquis of Moya, with whom he had three children.
In 1506 he married for a third time with María de Luna y Bobadilla, daughter of Alvaro de Luna, 2nd Lord of Fuentidueña.