García de Medrano y Álvarez de los Ríos (Valladolid, 20 July 1604 – 3 September 1683)[1] served as the Regent of the Kingdom of Navarre, Fiscal (Prosecutor), Mayor and Regent of Seville, Lord of San Gregorio, and a Professor at the University of Salamanca.

Their marriage was the root and origin of one of the most widespread families of legal professionals serving the Spanish monarchy during the 17th and 18th centuries.

His second son, Andrés de Medrano y Mendizábal, succeeded him as the 2nd Count of Torrubia after his elder brother died without heirs.

[5] In 1677, García de Medrano added a new construction or renovation to the Castle of San Gregorio, commemorated in stone above the entrance.

[2] In 1657, he presided over the Chamber of Magistrates in the Audiencia of Seville and was appointed by the king as a visitor and reformer to the University of Alcalá.

The reforms implemented marked the conclusion of the university's independence, a principle previously endorsed by the Catholic Church.

[13] In the year 1657, Don Garcia de Medrano presided over the Hall of Mayors of Castile and was visitor of the University of Alcalá.

At the conclusion of this period, individuals interested in competing for the chair would present themselves before the rector and councilors of the College of San Ildefonso.

Contestants selected their points based on seniority by degree and faculty, after which they were allocated twenty-four hours to prepare a Latin lecture, subsequently delivered on the assigned topic.

By the mid-eighteenth century, the council had shifted to allocating chairs solely based on seniority and college connections.

This professor would naturally enter the competition, be assumed as the sole candidate, and thus "repossessed" of their chair without a genuine contest.

[14] Furthermore, the powers of the cloister were confined by Medrano to matters related to granting degrees, waiving courses, and the minutiae of academic administration.

[18] However, it did possess the privilege to choose councilors from the faculties of theology, canon law, and medicine to represent its interests in the rector's deliberations.

Initially accommodating 36 students specializing in Latin and Greek, the number was later reduced to 16 following reforms implemented by García de Medrano.

[21] Together they had three sons: Garcia de Medrano's great-great-granddaughter Maria became Duchess of Gor, Grandee, by marriage.