In 1947, he procured a Bachelor of Arts degree from Washington University in St. Louis, Missouri.
After he was not nominated for United States Attorney, Eisele returned to private practice in Little Rock from 1956 to 1970.
[citation needed] In the early 1960s, Eisele supported Winthrop Rockefeller's attempt to revive the Arkansas Republican Party.
At the time Rockefeller was engaged in an intra-party rivalry with state chairman William L. Spicer of Fort Smith, the owner of a chain of drive-in theaters.
[3] Eisele was nominated by President Richard Nixon on January 23, 1970, to a seat on the United States District Court for the Eastern District of Arkansas vacated by Judge Gordon Elmo Young.