He made his debut for Derby at the age of 17 as a striker in a Premier League match against Sunderland in May 2002,[1] his only appearance that season.
[5] Twigg signed a two-year contract with Conference National side Oxford United on 5 July 2007.
"[6] He came on as a substitute on the opening day of the 2007–08 season at home against Forest Green Rovers in which he won and scored a stoppage time penalty to win the game for Oxford on his debut.
[7] An ankle injury that required surgery in October led to him missing seven weeks of the season before he returned to the side in December.
Twigg also played on the Shamrock Rovers team that was the first Irish club to reach the group stages of the UEFA Europa League.
[33] Twigg scored on his debut for Portadown in a match against Donegal Celtic at Shamrock Park on 5 January 2013, finishing the season with six goals from 11 league games.
[34] Twigg had signed a pre-contract agreement with Ballymena United with a view to joining the Sky Blues at the start of the 2016–17 NIFL Premiership season.
On 16 July 2016 it was announced that Twigg had rejected the offer of a new contract from Portadown and would be signing for Ballymena's derby rivals Coleraine.