Ayale was born in the village of Gojam in Ethiopia to Tabak (his father) and Tesfia (his mother), and is Jewish.

Fellow Israeli long-distance runner and Ethiopian Jew Girmaw Amare was born in the same area nine years prior.

[3] On July 13, 2017, at the 2017 Maccabiah Games in Jerusalem, Israel, in the 5,000 metre race Ayale ran it in 14:46.25, winning a silver medal.

[1] On July 24, 2019, at the Israeli Championships in Tel Aviv, Israel, in the 1,500 metre race Ayale ran a 3:48.81, winning a silver medal.

[1] In May 2022, in the European Cup in London, Ayale set a national record in the 10,000 metres, running 27:49.88 to become the first Israeli to break 28 minutes in the event.

[4][3] On August 15, 2022, Ayale won the bronze medal in the marathon at the European Athletics Championships held in Munich, Germany, with a time of 2:10:29, directly behind fellow Israeli Maru Teferi.

[6] He said, referring to the Munich massacre, "Fifty years after what happened here, winning a medal and waving the Israeli flag is just so sweet.

[11] Ayale has a younger brother, Yehuda Darba Ayala, who holds Israel's national U23 5,000 metres record.