Gaspésie–Îles-de-la-Madeleine (French pronunciation: [ɡaspezi il də la madlɛn]) is an administrative region of Quebec consisting of the Gaspé Peninsula (Gaspésie) and the Îles-de-la-Madeleine.

It lies in the Gulf of Saint Lawrence at the eastern extreme of southern Quebec.

[1] The region's interior, 80% of which is covered by coniferous forests, is among the most rugged terrain in the province.

Rich soils cover the land along the coast and within the region's river valleys.

Forty-two local municipalities are located in the Gaspésie–Îles-de-la-Madeleine region, along with seven unorganized territories, two reserves, and one Mi'kmaq community.