[3] Picking up immediately where Gatchaman II left off in storyline, the third and final series debuted a week later, running for 48 episodes.

Aspects such as the animation, music, and mecha designs were further overhauled with F. After Leader X is seemingly destroyed for good at the end of Gatchaman II, a fragment of him that survived grows and mutates into Z.

In the wake of Anderson's death, Dr. Nambu has become the new head of the ISO, while the team is now confined to the Gallatown (aka "G-Town") underwater base.

As the series progresses, it is learned that the radiation exposure from constant use of the Hypershoot is slowly killing Ken, and that continued use would mean death.

[6][7] Count Egobossler's name was changed to Happy Boy (for the grin-faced mask and his laughing) in the dub, and his origin was also rewritten.