After appearing in dance songs, Khan made her acting debut with Yash Raj Films's Rocket Singh: Salesman of the Year (2009).

[11] She appeared in a couple of music videos one of which, "Hawa Mein Udati Jaaye" by Bombay Vikings, became hugely popular.

Anupama Chopra said, "Gauahar was fashionable, ambitious and smart receptionist, she was sharply etched and memorable as Koena in the film".

[18] Khan played Chand Bibi in the 2012 romantic drama Ishaqzaade, in which she also appeared in two item numbers "Jhalla Walla" and "Chokra Jawaan".

Shomini Sen of Zee News stated that, "Gauahar as a kind-hearted prostitute Chand sizzles in two songs.

[citation needed] Khan took an exit after her boyfriend Kushal Tandon was asked to leave after he hit VJ Andy.

[22] In May 2014, Khan participated in Colors TV's stunt show Fear Factor: Khatron Ke Khiladi in its Fifth Season along with Kushal Tandon.

On 30 November 2014, Khan was slapped during the shooting of a singing reality show called India's Raw Star by a member of the audience who admonished her for wearing a short dress.

[28] In January 2016, Khan started the year with appearing in Ekta Kapoor's Kyaa Kool Hain Hum 3 for the item song "Jawani Le Doobi".

[29] In August 2016, Khan played one of the main leads in Ravi Agrawal's Fever, co-starring Rajeev Khandelwal and Gemma Atkinson as Kavya.

[37] In June 2019, Khan appeared in the Indian version of The Office, an adaptation of the hit BBC series of the same name.

[40] In 2020, she returned to Bigg Boss as a toofani senior for its fourteenth season along with Hina Khan and Sidharth Shukla for the first three weeks.