Lux played baseball for Indian Trail High School and Academy in Kenosha, Wisconsin.

[12] He was promoted to the Rancho Cucamonga Quakes of the California League for the 2018 season[15] and was selected to the mid-season all-star game.

[28] Lux was called up by the Dodgers to make his major league debut as the starting second baseman against the Colorado Rockies on September 2, 2019.

[32] On October 3, in his first at-bat in his postseason debut, Lux hit a pinch-hit solo home run off Hunter Strickland of the Washington Nationals.

At 21 years and 314 days old, Lux became the youngest player all-time to hit a pinch-hit home run in the postseason.

He was also the youngest Dodger to hit a home run in a postseason game, a record previously held by Cody Bellinger, who homered at age 22 years and 88 days during the 2017 NLDS against the Arizona Diamondbacks.

[34] He was not called back up to the Dodgers until the beginning of September[35] and played in only 19 games, hitting .175/.246/.349 with three homers and eight RBIs in 63 at bats.

[38] Lux became the full-time second baseman for the Dodgers in the 2022 season, playing in 129 games and batting .276 with six homers and 42 RBI.

[32] Lux hit .278 in the 2024 NLDS with one home run and three RBI[32] but struggled in the 2024 NLCS as a result of an injury that limited him only six at-bats.

[32] On January 6, 2025, the Dodgers traded Lux to the Cincinnati Reds in exchange for Mike Sirota and a competitive balance pick in the 2025 MLB draft.