During his fifteen-year career he played with the Detroit Tigers, Chicago White Sox, Washington Senators, Cleveland Indians and Cincinnati Reds.

Walker played in 1,784 major league games over 15 seasons with a career batting average of .294, with 1,991 hits, 124 home runs and 998 RBI.

After Hank Greenberg singled, Walker reached on an error but was caught off base when the catcher threw to first.

He did it in reverse order (called an "unnatural cycle") – starting with a home run, followed by triple, then a double and finally a single.

Despite Walker's strong performance that year, the Tigers (reportedly unhappy with his antics) traded him after the season.

The trade caused an uproar with Tiger fans, and owner Walter Briggs was forced to issue an announcement from his Miami home that "the deal was made with my approval."

He was survived by four sons, a daughter and two brothers, one of whom, Hub Walker, was also a former major league outfielder, with Detroit and Cincinnati.