Each short in the anthology has a distinctive animation style and unique story from the directors including Masaaki Yuasa, Shōji Kawamori, Shinichirō Watanabe, and Mahiro Maeda.
[4] In a barren desert, a man in a strange bird costume encounters a group of egg-like stones that burrow into the ground.
They create a giant pulsating brain in the ground (showcasing the title of the film) before panning out to reveal the bird-man again, who is standing in front of what appears to be a hive with the stones coming out of it.
After Sai is blown up and left with simply his head, Gonglong draws a superhero costume for himself and battles the robots; destroying many in the process.
However, he is unable to blow up the mother ship and Chase forces him to draw a missile to destroy it; saving the city, but making Gonglong cry due to his harshness.
He befriends a student at his school named Plåsse who wears a bag over his head and claims to be a superhero with super strength.
The doubles, who ambiguously seem to acknowledge his existence, continue to arrive at places before him, resulting in him becoming invisible to others, yet occasionally can be seen by people.
In this plotless segment, a salaryman, seemingly trapped in an endless cycle of work, makes an existential examination of the world.
An infant lives in a bright colorful nursery that caters to his every whim, only for it to suddenly break down; revealing a stoic and lifeless room.
With no other choice, Sho uses the grenade to blow up one of the gang leader's cars and the two flee before finally making it to the beach at sunrise.
The villagers all angrily attack it, but a young oni named Co-oni begins to hear strange noises emanating from it.
Soon, the other villagers join in by playing their own instruments as Jii turns into a wooden idol and leaves the rest up to his progeny.
Four inept criminals, Zico, Pekepeke, Yuki, and Mikishi, hear a word of a treasure located somewhere on Giant Island.
The boy suddenly finds himself in a fantastical and chaotic world where he does battle with a giant red ogre, gets saved by a dog (the titular Wanwa), drives a rocket car, and runs up a tree.
The boy looks out the window to see a stuffed Wanwa in a tree while a man in a trench coat arrives to leave flowers over a manhole cover of a dog.
When the end title pops up, the trench coat man is shocked that the short is over and is seen removing his outfit in a changing room.
In a steampunk world, a young woman illegally creates alien life forms inside stuffed animals.
The woman continues to run, but trips down a flight of stone steps and hurts her ankle while dropping the frog doll.
In what appears to be another dimension close to, yet different from ours, a young boy in a strange hood and helmet wanders a road where two gang bangers pull over and, presumably, beat him up.