Genuine Risk (February 15, 1977 – August 18, 2008) was an American Thoroughbred racehorse and broodmare best known for winning the 1980 Kentucky Derby.

Her dam Virtuous was descended from the British broodmare Iona, a half-sister to Ocean Swell and the grandmother of Tomy Lee.

Genuine Reward went to stud in 1997, sired 47 horses with 13 winners, and was in Wyoming until July 2015 when he was moved to Old Friends Equine in Georgetown, Kentucky, due to the philanthropic efforts of author Laura Hillenbrand.

Retired from breeding in 2000 after losing several foals or failing to conceive, Genuine Risk spent the rest of her life at the Firestone's Newstead Farm in Upperville, Virginia.

During Memorial Day Weekend in 2007, several hundred visitors visited Genuine Risk at Newstead during the annual Hunt Country Stable Tour, on what was to be her last public appearance.