Prior to his NFL career he played college football at Marquette University, which dropped its program after his junior season.
After a 3–6 season in 1960 under head coach Lisle Blackbourn, the university dropped the football program in December,[3] citing financial issues.
In his first season, he won the starting job at right defensive end (replacing Nate Borden) and also made the NFL All-Rookie team.
In the frigid 1967 NFL Championship Game against the Green Bay Packers, often referred to as the Ice Bowl, he picked up a Bart Starr fumble and ran it in for a touchdown, scoring six of the Cowboys' 17 points in the loss.
The NFL didn't recognize quarterback sacks as an official stat until 1982; however, the Cowboys have their own records, dating back before the 1982 season.
Andrie played defensive end for the Cowboys for 11 seasons, registering 112 straight regular-season starts and only two missed games in his career, with a dislocated elbow in 1963.
[17] Andrie worked with Cowboy teammate Lilly in a beer distribution business in Waco, before founding a promotional products company in 1979.