George Clarke (1676 – 12 January 1760) was a British colonial administrator and landowner who served as the acting governor of New York from 1736 to 1743.

Along with his wife he purchased land in 1715 in Hempstead, Long Island, New York, and built an estate called Hyde Park.

In 1741, Clarke was marginally involved in the suppression of the New York Conspiracy of 1741, a plot much-disputed by historians on the part of African slaves and poor white settlers to overthrow the colonial government by setting fires in New York City in March 1741.

On his return journey to England, with the fortune he had amassed in America, he was captured by a French Navy cruiser ship.

[4] The British athlete and politician Sebastian Coe is descended from George Clarke, who was his seven-times-great-grandfather, via a son who lived in Jamaica.