Working under the name George Deloy, he performed in plays and musicals at many of the major American regional theaters such as Seattle Repertory, American Conservatory Theater in San Francisco, Old Globe Theatre in San Diego, Cincinnati Playhouse, Mark Taper Forum in Los Angeles and Huntington Theatre in Boston.
Much of his work was in television – one of his first characters was Bert in the episode "Breakout to Murder" of the NBC crime drama series The Eddie Capra Mysteries in 1978, followed in 1979 by the role of Dr. Gilbert Kent on the TV miniseries The Seekers.
Elsewhere, L.A. Law, Nine to Five, Beverly Hills 90210, Walker, Texas Ranger, Home Improvement, Cheers, Frasier, and Superman: The Animated Series.
[2] DelHoyo has become noted as a voice-over artist, lending his voice to numerous Hollywood film trailers and network television promos.
He appeared in the Academy Award-winning animated feature Rango (2011) produced by Industrial Light & Magic and released by Paramount.