[1] The George H. Locke Memorial Branch of the Toronto Public Library, which opened in 1949, is named after him.

After graduating, he taught as a professor of ancient history at the University of Toronto and continued to teach at other colleges in subsequent years.

He served as editor of the School Review while at the University of Chicago and was also the author of books on Canadian history.

[7] In 1930, Locke, along with Mary J. L. Black and John Ridington, were hired as part of a commission of inquiry into the conditions of Canadian public libraries.

As part of the commission, Locke and the other commissioners toured Canada to visit and report on local libraries.