From 2002 until 2013, the team was a member of the Colonial Athletic Association (CAA).

The team plays its home games at George Mason Softball Complex located on the university's campus.

[4] George Mason qualified for the NCAA Division I softball tournament for the first time in 2023 after winning the Atlantic 10 Conference tournament, defeating Loyola Chicago by a score of 6-3.

[5][6][7] The Patriots faced off against Duke in their first game of the tournament, losing 2-1 in a close contest.

In 2010, James was named to the CAA's 25th Anniversary softball team.