George William Francis Sackville Russell, 10th Duke of Bedford DL (16 April 1852 – 23 March 1893) was a British peer and politician.

He was the son of Francis Russell, 9th Duke of Bedford and Lady Elizabeth Sackville-West.

In 1891, Russell inherited the title of Duke of Bedford, together with Woburn Abbey and several other estates which went with it, including Chenies, Buckinghamshire, and the Bedford Estate, a sizeable area of central London including Bedford Square, Russell Square, Bloomsbury Square and Covent Garden.

In 1893, at the age of forty, he died of diabetes, at number 37, Chesham Place, London, and was buried in the 'Bedford Chapel' at St. Michael's Church at Chenies.

His titles and estates were inherited by his younger brother Herbrand Russell.