As a teenager, he became a DJ at a Meridian radio station, WOKK, and recorded his first discs for Carol Rachou's La Louisianne and Tamm labels in the mid 1960s.
[3] Soulé started plugging his songs, often written with his friend Paul Davis, to music publishers in Memphis and Nashville.
Among their best-known songs are "How Many Times", recorded by Mavis Staples, and "You Can't Stop a Man in Love", cut by Carl Carlton.
35 in Billboard's R & B chart the following year, spawning a successful reggae cover version from Freddie McGregor and crossing the Atlantic to become a massive hit on British dancefloors.
The song was featured on the nationally syndicated TV show Soul Train and caused a mild sensation when listeners realized that George Soulé was a white singer.
He received the Country Music Association's song of the year award for his engineering and mixing of Narvel Felts hit "Reconsider Me".
Soulé left music in the late '70s to work in the family iron smelting business in Meridian, returning to Muscle Shoals in 1987 as an announcer on WQLT FM radio.