He was also named the 2017 World Series Most Valuable Player (MVP), hitting a record-tying five home runs, as the Astros defeated the Los Angeles Dodgers in seven games.

He played on the varsity baseball team as a freshman despite standing 5 feet 2 inches (1.57 m) and weighing 100 pounds (45 kg).

[13] Splitting the 2013 season between Corpus Christi and the Oklahoma City RedHawks of the Class AAA Pacific Coast League, Springer joined the 30–30 club, recording more than 30 home runs and stolen bases.

During spring training in 2014, Springer and his agent rejected a reported seven-year contract worth $23 million, despite having not yet reached the major leagues.

He hit for a .353 batting average and a .647 slugging percentage before being called up to the major league team in time for their April 16 game.

[20] Springer made his MLB debut on April 16, 2014, at Minute Maid Park against the Kansas City Royals.

Batting second and playing right field, Springer collected his first career hit, an infield single, against Royals pitcher Jeremy Guthrie.

Springer hit the first home run of his MLB career on May 8, 2014, at Comerica Park off Detroit Tigers pitcher Drew Smyly.

[citation needed] On July 23, 2014, Springer was placed on the 15-day disabled list due to a left quad strain.

[22] During a game against the Texas Rangers on April 12, 2015, Springer robbed Leonys Martín of a potential game-winning grand slam by making a leaping catch by the wall in the 10th inning at Globe Life Field.

[23] On June 10 versus the Chicago White Sox, Springer attained his first career five-hit game, the first for an Astro since Brandon Barnes on July 19, 2013, who hit for the cycle in that day.

After consistently cutting down on his strikeout rate from his rookie year, Springer improved the quality of his at bats enough in 2016, that by May, the Astros made him their regular leadoff hitter.

He also made his first MLB All-Star team played at Marlins Park in Miami, elected by the fans as a starter.

[27] On September 29, prior to a game against the Boston Red Sox at Fenway Park, Springer met and reunited with his first-grade teacher.

In all, Springer hit five home runs, tying the World Series record shared by Reggie Jackson and Chase Utley.

[32] After the season, Springer was named an American League Silver Slugger Award winner at outfield for the first time in his career.

Illegal sign-stealing had been rampant throughout major league baseball, but the resulting scandal focused mostly on the Astros, who had won the World Series that year.

He had homered off Mariners pitcher Felix Hernandez in the first inning of Opening Day 2017 at Minute Maid Park.

Springer went back-to-back with teammate Alex Bregman and hit what would be the deciding home run in the top of the 10th inning at Nationals Park to help lead the American League to an 8–6 victory.

[38] The Astros struggled through August with injuries to Springer, Carlos Correa, and Jose Altuve keeping them out of the lineup.

Springer returned to action on August 17 and the Astros held off the charging Oakland A's to win their second straight American League West Division title.

Springer started the 2018 postseason off on a strong note, hitting a home run off of Corey Kluber in Game 1 of the 2018 American League Division Series.

Springer then hit two more in Game 3 of the ALDS off of Mike Clevinger and Cody Allen respectively, leading the Astros to an 11–3 victory and a series sweep of the Cleveland Indians.

On May 1, Major League Baseball disciplined Springer for an anti-gay slur directed at umpire Ángel Hernández, which was caught on camera during a game on April 23.

[41] Carrying a .316 batting average, 1.046 OPS, and 18 home runs through June 28, Springer was named a starting outfielder for American League in the All-Star Game.

[46] While on the injured list, Springer made his first return to Houston as a Blue Jay in an early-May series, and received a standing ovation.

[52] In 2022, Springer received his fourth All-Star selection and helped lead the Blue Jays to a Wild Card berth.

Springer, along with Matt Chapman, got two hits during the first game of the 2022 American League Wild Card Series against the Seattle Mariners.

Springer's father, George Jr., competed in the 1976 Little League World Series and played college football for the UConn Huskies.

[22] He began to perform charity work as a spokesperson for the Stuttering Association for the Young (SAY) while in Houston, which included hosting an annual bowling benefit among other things.