[6] His father was a Greek Orthodox priest and dean emeritus of the Archdiocesan Cathedral of the Holy Trinity in New York City.

[7] Following some time in Purchase, New York, Stephanopoulos moved to the eastern suburbs of Cleveland, Ohio, where he graduated in 1978 from Orange High School in Pepper Pike.

[8] In 1982, Stephanopoulos received a Bachelor of Arts degree in political science summa cum laude from Columbia University in New York and was the salutatorian of his class.

[12] Stephanopoulos attended Balliol College at the University of Oxford in England, as a Rhodes Scholar, earning a Master of Arts in Theology in 1984.

Stephanopoulos called NBC journalist Tim Russert, CNN chairman Tom Johnson, as well as several others, whom he convinced to keep her conference off television.

White House press secretary, Mike McCurry, said that President Clinton told Stephanopoulos "not to worry about" the accident but to get his license renewed.

In the book, Stephanopoulos spoke of his depression and how his face broke out into hives due to the pressures of conveying the Clinton White House message.

Stephanopoulos describes Clinton in the book as a "complicated man responding to the pressures and pleasures of public life in ways I found both awesome and appalling".

In September 2002, Stephanopoulos became host of This Week, and ABC News officially named him "Chief Washington Correspondent" in December 2005.

[44] During the 2008 presidential election campaign, Stephanopoulos launched a blog George's Bottom Line on the ABC News website.

However, after his successor, Christiane Amanpour, left the show amid sagging ratings, it was announced that Stephanopoulos would return as host of This Week in December 2011.

During the debate, Stephanopoulos repeatedly asked Romney whether the former Massachusetts governor believes the U.S. Supreme Court should overturn a 1965 ruling that a constitutional right to privacy bars states from banning contraception.

Stephanopoulos leads a new documentary unit for Disney's digital platforms and hosts four primetime hour-long specials on the ABC network annually.

[49] In 2009, Stephanopoulos spoke at the annual Tri-C Presidential Scholarship Luncheon held at the Renaissance Cleveland Hotel and praised Cuyahoga Community College.

In 1994, columnist Jack Anderson reported that Stephanopoulos signed an $835,000 commercial real estate deal consisting of a two-story apartment, including an eyewear retailer, with a below-market loan rate from a bank owned by Hugh McColl, who had been called by President Clinton "the most enlightened banker in America".

At the time the loan commitment was made, Mr. Anderson (or his imaginary 'George Smith' who 'doesn't work in the White House') could have walked into any NationsBank Mortgage Company office in the D.C. area and received the same excellent rate and term for the same deal.

[57] The donations had been reported by the Clinton Foundation, which Stephanopoulos had considered sufficient, a reliance ABC News characterized as "an honest mistake".

[59] In the month prior to the revelation of his donations, Stephanopoulos told Jon Stewart on The Daily Show that when money is given to the Clinton Foundation, "everybody" knows there's "a hope that that's going to lead to something, and that's what you have to be careful of.

"[59] In 2010, Stephanopoulos attended a dinner party at the home of convicted sex offender socialite Jeffrey Epstein alongside Chelsea Handler, Woody Allen, Katie Couric, Prince Andrew, Charlie Rose and Eva Andersson-Dubin.

Fox's character, Lewis Rothschild, in the film The American President (1995), written by Aaron Sorkin was modeled after Stephanopoulos.

He was also used by Sorkin as the model for Rob Lowe's character, Sam Seaborn, on the television drama series The West Wing.

[75] In 2000, he rivaled John F. Kennedy Jr. as the nineties' most eligible non-Hollywood bachelor, appearing (along with George Clooney) in a People magazine's "Most Wanted" list.

[76] Stephanopoulos appeared in the Pawn Stars episode "Buy the Book", where he bought a first edition of Ernest Hemingway's For Whom the Bell Tolls for $675.

[82] In July 2022, Loot's episode 4 of season 1 was released, in which main character Molly Novak said, "sometimes I turn on the news and pretend George Stephanopoulos is my husband.

[84] Stephanopoulos married Ali Wentworth,[85] an actress, comedian, and writer, in 2001 at the Archdiocesan Cathedral of the Holy Trinity on New York's Upper East Side.