Tsamis attended Stetson University, where he played college baseball for the Hatters under head coach Pete Dunn.

[3] Tsamis was a replacement player with the Los Angeles Dodgers during spring training prior to the 1995 season.

The strike was resolved at the end of spring training, and Tsamis returned to the minor leagues, where he pitched until 1998.

Tsamis managed through Saints through the 2020 season, after which they left the American Association and became Triple-A affiliates of the Minnesota Twins.

In 2024, the Cougars would make the playoffs for the third year in a row with a 55–45 record this time sweeping the Lake Country DockHounds in the first round, sweeping the Chicago Dogs in the East Division championship series, and sweeping the Winnipeg Goldeyes in the Miles Wolff Cup Final bringing home the Cougars' third title in franchise history and their first Miles Wolff Cup since joining the American Association.

[7] Tsamis recently managed the North Division in the American Association All-Star Game in Sioux Falls, SD.