[2] He originally belonged to the African Methodist Episcopal Church but converted to Catholicism when he was a child while attending a parochial school in Baltimore, Maryland.

[2] After completing his period of novitiate in 1974, Murry obtained a Master of Divinity degree from the Jesuit School of Theology at Berkeley in Berkeley, California, and a Masters and Doctorate in American Cultural History from George Washington University in Washington, D.C. On June 9, 1979, Murry was ordained to the priesthood by Archbishop William Donald Borders in the Jesuit province of Maryland.

[2] Cardinal Joseph Bernardin served as the principal consecrator, assisted by Auxiliary Bishops Alfred Abramowicz and Timothy Lyne.

[2] In September 2015, Pope Francis appointed Murry to the Synod of Bishops that met in October 2015 to discuss family life.

Murry said he supported greater participation from theologians, cultural historians, and other experts, and that the Synod needed to find a way to hear the voices of the people who were the subject of its discussions.

[17] Murry submitted his resignation as bishop of the Diocese of Youngstown to Pope Francis on May 26, 2020, four years before the mandatory retirement age of 75.

[17][18] George Murry died on June 5, 2020, a few days after being admitted to Memorial Sloan Kettering Cancer Center in New York City for treatment.