At age 21 he began studying to become an attorney at the law offices of Buckland and Hayes (later President Rutherford B. Hayes); he was admitted to the bar two years later and established a moderate law practice, earning a reputation as a hard-working lawyer.

Elected to the Kansas State Legislature in 1862, he served for 14 of the next 18 years and was Speaker pro tempore in 1876.

After 15 years of civic service, George Glick was forced to abandon his political career because of a throat infection that nearly destroyed his ability to speak.

He also managed his farm and served as a charter member and first vice president of the Kansas Historical Society.

[5] In 1914, the state of Kansas donated a marble statue of Glick to the U.S. Capitol's National Statuary Hall Collection as one of its two allowed entries.