He is believed to have studied with Calvin Ryder, a Maine native who designed several buildings in Bangor.
One of his first works, the Adams-Pickering Block in Bangor, is the largest surviving project in Maine.
In winter 1878, he left Bangor and moved west, settling in Minneapolis in spring 1879.
He was soon joined by his brother, Fremont D. Orff, who worked as a draftsman until they formed a partnership in 1881.
A number of his works are listed on the United States National Register of Historic Places.