Apart from a large number of salon pieces for the piano, he was also known as an accompanist to popular theatrical performances including puppet plays.

[2] In contrast, the online catalogue of the French national library (Bibliothèque nationale de France), counts 503 entries under his name, which also includes arrangements of Lamothe's works by other composers.

His parents were Jean Paul Émile Alexandre Lamothe, a lawyer, and Marie Madeleine Désirée, née Chatelain.

[6] An 1882 newspaper notice mentions him as giving teaching courses on the "orgue-harmonium" in the Salons Mangeot, 21 avenue de l'Opéra, Paris.

In 1864, Lamothe became a member of "Les Pierrots", a Parisian group of artists convened by the actor Montrouge, alongside Jean-François Berthelier, Coquelin Cadet, Joseph Darcier, Léon Fusier, Félix Galipaux, Eugène Silvain, and others.

As composers who wrote specific music for his plays he included, besides Lamothe, Charles Domergue de la Chaussée, Olivier Métra, Émile Pessard, and Albert Renaud.